Glossary

Ethics Committee (CEP / CEI / IRB)

The local body that reviews trial ethics, informed consent quality, and subject protection.

What it means

In LATAM, ethics review is decentralized: CEPs in Brazil, Comités de Ética en Investigación (CEI) across Spanish-speaking countries, and site-level IRBs. Each reviews the ICF and recruitment materials in the local language and can require site-specific edits before granting approval.

Why it matters for LATAM submissions

Ethics committees, not regulators, are usually the ones that read the ICF word-by-word. Translation quality at the consent level is where studies live or die on timeline.

Relevant regulators

ANVISACOFEPRISANMATINVIMADIGEMIDARCSAISPMINSA

Related terms

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